Rapid cooling can greatly reduce post-ischemic injury after cardiac arrest and is considered vital in cryonics cases. ^{1, 2}

Extracorporeal bypass, implemented with the Air Transportable Perfusion system (ATP), enables the fastest possible cooling by circulating blood outside the body through a heat exchanger.  However, extracorporeal bypass entails time-consuming surgical procedures.  Liquid ventilation uses the lungs as heat exchangers by pumping a chilled liquid and gas mixture into them, cooling the blood. This cooling method is nearly as efficient as extracorporeal bypass, without requiring surgery.³  A portable device capable of delivering liquid ventilation to a cryonics patient immediately after cardiac arrest would represent a major breakthrough in stabilization technology and a new standard of care.


References

1. Kochanek and Safar. Therapeutic hypothermia for severe traumatic brain injury.  JAMA: 2003; 289: 3007-3009.

2. Lampe JW, Becker LB. Rapid cooling for saving lives: a bioengineering opportunity. Expert Review of Medical Devices: 2007
Jul; 4(4): 441-446.

3.  Harris SB, Darwin MG, Russell SR, O'Farrell JM, Fletcher M, Wowk B. Rapid (0.5 degrees C/min) minimally invasive induction of hypothermia using cold perfluorochemical lung lavage in dogs.
Resuscitation: 2001 Aug; 50(2): 189-204.